Madikwe is home to 66 mammal species including the Big Five and approximately 300 resident and migrant bird species. It is one of South Africa's largest game reserves.
The Madikwe Game Reserve, situated against the Botswana border, 90 km north of Zeerust, just four hours' drive from both Johannesburg and Pretoria, is now one of South Africa's prime safari destinations. Madikwe is a Big Five game reserve covering some 75,000 hectare, (185,000 acres). It is one of the largest game reserves in South Africa. The rich diversity of vegetation ensures a wide range of game and the topography offers ideal game viewing opportunities.